Adaptation of the cardiac muscle of broiler chicken when using immunomodulatory drugs

The paper discusses various aspects of the effects of immunomodulatory drugs (“Gamavit” and “Fosprenil”) on the histological and morphological structure of the heart muscle of broiler chickens, morphological and functional patterns of adaptation of the organ. On poultry farms during the production of meat products broiler chickens are used. Their diet often includes immunomodulatory drugs, which influence at the cardiovascular system, at this stage, is not elucidated enough in the modern academic writing. The use of drugs in the poultry industry for the accelerated development of broilers in some cases can lead to various forms of cardiac hypertrophy, due to rapid development of the bird. The study of stress mechanisms of the microvasculature in the application of high doses of drugs for the accelerated development of broilers showed, that various tissue and ultrastructural changes associated with the predominant participation of the metabolic and circulatory factors can occur in heart muscle. Research methods: histological and morphometric methods were used in the paper. In the process, information was obtained on the effect of immunomodulatory drugs on cardiac morphogenesis in postincubatory ontogenesis of broiler chickens. The prospects of the use of these indicators are in the optimization of feeding norms of broilers and making of their rations. The importance of determining the effect of these drugs is due to the central role of the heart in the circulatory system and the dynamics of its pumping function in various forms of myocardial hyperfunction in the course of overload and hypertrophy. The influence of immunomodulating drugs on the heart muscle, morphological and functional adaptation of laws allows to determine best support practices of the cardiovascular system.