Alzheimer's disease: biophysics, genetics, epigenetics, neuroimaging, bioelementology, nutriciology, treatment, prevention and neurotrenching

The complex more than Alzheimer’s disease 115-year-old problem paradigm is an author’s multidisciplinary response through the prism of fundamental applied algorithms/tools/technologies to the pathogenesis, diagnosis, treatment and prevention of this neurodegeneration. Homo sapiens brains are biological, biophysical, neurophysiological and medico-social information exchange paradigms. The achievement of research N. P. Romanchuk is the establishment of many genetic and epigenetic factors of cognitive decline and neurodegenerative diseases. The introduction of copyright developments in the last 15 years has made it possible to form a system of algorithms and tools for managing neuroplasticity. Modified combined EEG/PET and PET/fMRI methods and hybrid PET/CT/MRI technologies are combined functional and structural neuroimaging. Modern communications are multilevel, multiparadigmal, and interdisciplinary models of information exchange. Neurogenetics is a center for multidisciplinary and interagency research using best practices, involving 5P Medicine and 5G technology. In studies, N.P. Romanchuk showed that for the new neurogenesis and neuroplasticity, for the management of human neuroplasticity and biological age, for the modern neurophysiology and neurorehabilitation of cognitive disorders and cognitive disorders, sufficient functional and energy nutrition of the brain is necessary using modern neurotechnologies of nuclear medicine. Modern artificial intelligence technologies are capable of many things, including predicting cognitive impairment and cognitive disorders, using combined and hybrid neuroimaging, sequencing of a new generation, etc., in order to begin timely and effective rehabilitation of the H. sapiens brain. The brain of H. sapiens is the next frontier for healthcare. The merger of combined and hybrid neuroimaging methods with artificial intelligence technologies allows us to understand and diagnose neurological disorders and find new methods of rehabilitation and medical and social support that will lead to improved mental health. The severity of cognitive impairment largely depends on the time of early prevention, the severity of depressive disorder, the age of the patient, neuroendocrine, cerebral and cerebrovascular pathology.