Analysis of chromosome aberrations and micronucleus in the descendants of Chinese hamster cells, irradiated at various doses and intensities of Y-radiation

The Chinese hamster cells V-79 were irradiated by y-rays in doses 0.5 Gy and 3 Gy at dose rate of 0.48 Gy/min (an acute irradiation) and in dose 0.5 Gy at dose rate of 0.0485 MGy/min (a prolonged irradiation). The acute and prolonged irradiation in a dose 0.5 Gy enlarges frequency of appearance of micronucleus. Subsequent cultivation of the irradiated cells during 20 generations enlarges frequency of micronucleus, and for a prolonged irradiation the boosted frequency of micronucleus is saved during 40-60 generations. After an acute irradiation the number of micronucleus starts to be reduced after 20 generations. An acute and prolonged irradiating in a dose 0.5 Gy enlarge frequency of chromosome aberrations at once after an irradiating, which is gradually reduced up to a control level to 20 generating. The irradiating in a dose 3 Gy enlarges frequency of chromosome aberrations at once after an irradiating, which is reduced up to a control level to 20 generating, then increases to 40-th generating and remains at this level before 60-th generating.