Antibiotic sensitivity and antibiotic resistance of pathogenic and conditionally pathogenic enterobacteria allocated from the intestines of newborn calves

Diseases of newborn calves with acute intestinal infections occupy one of dominant positions in in-fectious pathology of bacterial etiology. The aim of the study was the investigation of antibiotic suscep-tibility and antibiotic resistance of pathogenic and conditionally pathogenic microflora of the intestine of newborn calves with clinical signs of intestinal infection. 32 tests of biological material from new-born calves with clinical signs of intestinal frustra-tion were subjected to bacteriological research. Morphological and cultural properties of the isolates emitted from biomaterial studied by crops on usual and special environments with subsequent incuba-tion in the thermostat at the temperature of 37 °C during 18-24 hours. Microorganisms' identification was carried out with use of "Determinant of bacteria of Berdzhi". The main causative agents of intestinal infections of newborn calves were the following representatives of Enterobacteriaceae family: 5.4 % - Proteus mirabilis; 19 - Escherichia coli; 9.5 - Proteus vulgaris, Enterobacter aerogenes; 4.8 % - Yersinia enterocolitica and Klebsiella pneumonia. Polyresistance to antibacterial prepara-tions cultures was shown by Proteus vulgaris, Enterobacter aerogenes and Klebsiella pneumonia, moderate resistance - by Escherichia coli, Proteus mirabilis and Yersinia enterocolitica. The cultures of opportunistic Escherichia coli were resistant to erythromycin (95.2 %), tetracycline and penicillin (90.5 %), canamycin (85.7 %), ampicillin (76.2 %), streptomycin and gentamicin (71.4 %). Most cul-tures of Escherichia coli showed sensitivity to polymyxin (85.7 %), ciprofloxacin and enrofloxacin (71.4 %), less to levomycetin - 66.7 %. 71.4 % of opportunistic strains of Escherichia coli possess polyresistance. Monoresistant strains of Enteroba-cteriaceae family representatives were not re-vealed.