Antimicrobial activity of anticaries toothpastes for children of early age

Aim: evaluation of antimicrobial activity of toothpastes with different component composition recommended for early-aged children. Material and methods. The study material comprised dental plaque of patients under the age of 3 years with decompensated caries. Seven toothpastes with different composition for children aged from 0 to 3 years were studied. Identification of the isolated microorganisms was carried out by mass spectrometry. Antibacterial activity was determined by diffusion into agar and serial dilutions. Results. Pastes containing xylitol, lactic enzymes and components of medicinal herbs showed the absence of a zone of inhibition of the growth of microorganisms. Fluoride pastes are active against all tested microorganisms. In this case, the inhibiting final concentration of fluorine was 0.00016–0.0025 %, depending on the concentration of fluorine in the paste. Conclusion. The least antimicrobial activity had complex pastes with dairy enzymes and components of medicinal herbs, as well as samples with xylitol. Simple toothpastes with organic and inorganic fluoride compounds had the greatest bactericidal effect.