Aseptic instability of the hip endoprosthesis in patients with coxarthrosis

Research Objective - study of bone tissue remodeling features at aseptic instability (АI) of the femoral endoprosthesis in patients with coxarthrosis according to a level of biomechanical markers of bone resorption and formation. 41 patients with coxarthrosis have been examined, a primary total hip replacement was carried out in 27 patients of them (the comparison group), the endoprosthesis re-replacement was performed in 14 patients of the basic group with endoprosthesis АI. Among the examined patients there were 20 men and 21 women aged from 46 to 67. The control group contained 13 donors. All the patients were made double-energy x-ray absorptiometry, formation markers (osteocalcin and alkaline phosphatase bone isoenzyme) and bone resorption (С-terminal first type collagen telopeptide) and calcium - phosphoric metabolism state were determined. The significant data were considered to be the data with probability index р