Рregnant women with acute cytomegalovirus infection

A pregnant women with acute cytomegalovirus (CMV) infection were examined. CMV infection was diagnosed by the detection of anti - CMV IgМ (by the enzyme immunoassay)or DNA by PCR in the blood. The immunophenotype of lymphocytes CD+3, CD4+, CD8+, CD16+,CD19+, IgG, IgМ, IgA and the spontaneous production of TNFa and IL-8 in the blood were studied. In pregnant women with CMV infection the presence of the immunosuppression of cell - mediated immunity reactions, the hyperproduction of Fc-receptors of natural killers, B lymphocytes (CD19+), the hyperglobulinemia of serum IgM and IgG, as well as the increased synthesis of proinflammatory cytokines - TNFα and IL-8 - were established.