Non-contact measurement of local concentration and the local temperature of magnetic nanoparticles inside of a living organism (short message)

This paper proposes a method of measuring the local concentration N and the local temperature T of the magnetic nanoparticles inside a living organism by means of magnetic resonance imaging, operating with two inductions of magnetic field В 1 ˃ 3k Т and B 2 1/ P , T = P · B 2 / (k·ln ( M 1/ M 2)) (k - Boltzmann constant, P - the magnetic moment of the nanoparticles, M 2, M 1 - the magnetizations measured in the inductions B 2 and B 1). The method is aimed to control the movement of nanoparticles through the body's vessels and their delivery to the target tissue, as well as to control the local temperature of the nanoparticles near the target tissue in order to ensure their heating to the optimum temperature. The use of a magnetic resonance tomograph makes it possible, using its gradient coils, to create a inhomogeneous magnetic field that transports nanoparticles to target tissues throughout body vessels.