Biochemical assessment of the condition of patients with achondroplasia for limb lengthening

Within the framework of clinical studies the condition of children with achondroplasia has been analyzed biochemically before treatment and during bifocal cross lengthening of femur and leg. Serum phosphomonoesterases activity in patients with achondroplasia has been revealed to be reliably higher in comparison with the analogous values in normal children of the same age. The level of electrolytes in children with achondroplasia does not exceed the bounds of physiological norm in spite of bone metabolism disorders.