Effect of exopolysaccharides of lactic acid bacteria on burn healing in rats

The aim of the paper is to study the effects of exopolysaccharides (EPS) of lactic acid bacteria Lactococcus lactis B-1662 and Streptococcus thermophilus on burn healing in female white rats. Materials and Methods. We used EPS of Lactococcus lactis B-1662 and Streptococcus thermophilus, 5 % dexpanthenol. Experimental animals (female white rats) were divided into 5 groups: Group 1 - without burns, Group 2 - with burns, Group 3 - burns treated with 5 % dexpanthenol, Group 4 - burns treated with 0.6 % solution of EPS of L. lactis B-1662, Group 5 - burns treated with 0.6 % solution of EPS of S. thermophilus. The 3rd-degree burns were simulated under ether anesthesia on the interscapular space with the test glass filled with boiling water (2/3 volume; 30 seconds). To determine the microflora, washings were taken daily from the burn surface during the experiment (28 days). Results. The animals belonging to Group 2 demonstrated the reduction of the crustlike surface of a healing skin lesion in 10 days, but the complete burn healing and restoration of the body hair coat was observed only after 28 days...