Diagnostic informativity of cytokines/chemokines and growth factors in dentistry

The development of inflammatory processes occurs when processes of intercellular interaction with the participation of cytokines, chemokines and growth factors contained in biological fluids of the oral cavity are disrupted. The purpose of the study is to determine the diagnostic significance of the level of cytokines/chemokines and growth factors in various biological fluids of the oral cavity. Materials and methods of research. 4 groups of 20 (total 80) people were examined: 1 - with intact periodontium; 2 - with periodontitis; 3 - with dental implants in the dynamics of orthopedic treatment; 4 - after tooth extraction. The examination included the determination of hygienic and periodontal indices, and during tooth extraction - pain, swelling, hyperemia, and epithelization of the socket. Laboratory studies included determination of proinflammatory cytokines/chemokines and vascular endothelial growth factor (VEGF).