Dynamic changes of the anterior chamber produced by intravitreal injections of anti-VEGF drug

Rationale: Intravitreal injections (IVI) of antivascular endothelial growth factor (anti-VEGF) have become the mainstay in the treatment of neovascular age-related macular degeneration (nAMD). Llarger number of injections and the presence of a native lens lead to a change in the parameters of the iris-lens diaphragm and are links in the violation of the hydrodynamics of the eye. Objective: evaluate changes in the parameters of the anterior chamber after 3 IVI of the anti-VEGF drug in patients with a native lens and in patients with an intraocular lens (IOL). Methods: The study included 34 patients with nAMD, who were divided into 2 groups: group 1 - 17 people with a native lens and group 2-17 people with IOL. IOP was measured with an ICare Pro before IVI (T0), 1 minute after IVI (T1), 30 minutes (T2), and 180 minutes (T3). Using a Revo NX tomograph (Optopol, Poland), the anterior chamber depth (ACD) and angle of the anterior chamber were assessed. Results: ACD before treatment was statistically deeper in patients in group 2 (p