Dynamics of accumulation of autoantibodies to NMDA-receptors and protein S-100 in full term newborns born in asphyxia

The purpose of our study was determination of the level of autoantibodies to NMDA-receptors and protein S-100 in reported newborns born in asphyxia depending on the degree of gravity of previous hypoxia, respiratory disorders, the basic neurologic disturbances. We examined 47 full term newborns of the core group and 25 practically healthy of the control group. Normal indices of antibodies for protein S-100: 0-0,003OD, in NMDA-test: 0-0,02OD are determined. The predictors of the development of cerebral ischemia in newborns are revealed. Dependence between the level of antibodies to NMDA-receptors and protein S-100 and the severity of the condition of the newborn is proved.