Pharmacokinetics of antibiotics in experimental gunshot wounds

Experimental studies on the pharmacokinetics of gentamicin were performed on 40 rabbits with various methods of injection after the infliction of gunshot wounds of extremities. The results showed that the method of lymphotropic antibiotic therapy provides a more stable and long-term saturation of blood. The highest and the longest retaining concentration of gentamicin in the lymph nodes and soft tissue of gunshot wounds reached at lymphotropic method of injection.