Functional status of adrenal cortex glands at surgical correction of congenital heart disease under different anaesthesiological protections

Using fluorometric method the functional status of the adrenal cortex glands has been investigated among 98 patients with "cyanotic" and "pale" congenital heart diseases (CHD) having been operated without hypothermic perfusion protection (70 patients) and under the condition of hypothermic 1 perfusion (28 patients). It has been established that the operations on the "open" heart in the cases of non-complicated operative and post-operative periods are accompanied by the moderately expressed adreno-cortical reaction the activity of which depends on the degree of the initial state of patients, type of narcosis, the method of anaesthesiologic maintenance. Moderate growth (2-2.5) of the level of glucocorticoid hormones reflects an adequate adreno-cortical reaction ("stress-norm") of anaesthesiologic maintenance. The decrease of hormone response having been revealed in the post-operative time among the patients with complicated development is the evidence of exhausted hormonal reserve and is a symptom of an unfavorable prognosis. Such patients need to be provided by inotropic support and substitutional therapy immediately after the operation.