Hemoreological properties of blood and endothelial dysfunctions at hemorrhoids

The aim of our research was examination of endothelial function and hemoreological parameters of blood of patients with various forms of hemorrhoids. The study involved 78 patients, in which there were 66 patients with various forms of hemorrhoids, and 12 patients in the control group. Markers of endothelial dysfunctions (test with reactive hyperemia, concentration desquamated endothelial cells), indicators of functional activity trombocites before the treatment and 7-10 days after were analyzed. Consequently significant endothelial abnormalities were detected in main panel by the method of indirect estimation whereas quantity of desquamated endothelial cells between patients of main and control panel had no considerable difference. Normalization of quantity of desquamated endothelium cells have been recorded with ascension of endothelium level due to after treatment test with reactive hyperemia. More stable picture of functional indicators of trombocites activity and high rates of their recovery occurred among the patients who received flavanoids in postoperative period. Therefore the place of endothelial abnormalities and hemoreological malfunction in hemorrhoids development was defined and reasonability of using medicines affecting hemoreological indicators and functional activity of endothelium cells of patients with various hemorrhoids' forms was explained.