Genotoxic and cytotoxic effects in the buccal epithelium of medical personnel occupationally exposed to low doses of ionizing radiation

The article evaluates the genotoxic and cytotoxic effects of exposure to low-dose radiation on the buccal epithelium and their impact on the aging process of medical personnel working under exposure to low doses of ionizing radiation. It was found that in this group there are 1.9 times more people with accelerated aging, and genotoxic effects are manifested in a decrease in number of normal cells, an increase in the number of cells with genotoxic effects. An assessment of the biological age and the formation of nuclear anomalies corresponding to it suggest that under the conditions of exposure to ionizing radiation, medical personnel experience accelerated aging and strain on adaptation mechanisms, and, accordingly, an increase in the risks of long-term consequences from low doses of ionizing radiation.