The histochemical description of placental cells of female rats with experimental liver lesion

We studied the substances content in placental cells of rats with experimental paracetamol-induced liver lesion in a study using histochemical method. We revealed total proteins, glycogen, lipids, succinate dehydrogenase and alkaline phosphatase expressed as optical density in conventional units on paraffin and frozen sections. The findings suggest that liver lesion in the experiment causes changing of substances content in trophoblast of labyrinth, as well as in giant and spongiotrophoblast cells of the basal zone. We revealed a reduction of the optical density of total proteins, carbohydrates and succinate dehydrogenase in the cytotrophoblast cells of the labyrinth zone. In addition, we found a decrease in the content of total lipids, glycogens and succinate dehydrogenase in spongiotrophoblast and giant cells of the basal zone.