Histostructure of the wall of the human great saphenous vein wall in health and variceal transmation

The paper presents the study of the histological specimens of the great saphenous vein (GSV) biopsy pbyained post-mortem from individuals of both sexes of 35 to 70 years of age. The study group1 inclubed the specimens of grossly unchanged GSV (n=17), while group 2 consisted of GSV with multiple varices (n=31). The aim of the research is to obtain data on the wall histostructure for the intact and transformed GSVs. Results. The GSV wall has a thick circulation layer of smooth muscle cells and 10-16 intimal pads capable complete blocking the vein lumen. In the areas where «valves» were by duplex scanning, endothelial were observed. Most likely, their function is to retard the GSV iumen growing when the body is in the uhright position.