Chronic obliterating diseases of the arteries of the lower extremities. Modern outpatient treatment

Chronic arterial occlusive disease of the lower extremities (CAODLE) account for up to 20% of the total volume of cardiovascular pathology. The human and economic costs of this disease are very high. The main principle of the treatment of Chronic arterial occlusive disease of the lower extremities is the continuity and use of all available pharmacological and non-pharmacological methods of treatment, which are aimed at reducing the risk of developing any complication from the cardiovascular system, progression of lower limb ischemia, as well as eliminating its clinical manifestations - intermittent lameness. Thanks to modern and affordable diagnostic methods, such as ultrasound duplex vascular scanning (USDS), there are more and more opportunities for early detection of asymptomatic course of obliterating atherosclerosis of the lower extremities. For patients with CAODLE, long-term antiplatelet therapy, smoking cessation, lipid-lowering therapy, as well as diabetes and hypertension therapy are recommended. The article shows that in the world evidence base there is more and more data on the effective use of statins, cilostosal and combined antiplatelet and antithrombotic therapy after surgical treatment. The introduction of these treatments remains a challenge due to the high cost and burden of polypragmasia and requires further research.