Immunology: immune response as leading protection factor against cancer

The prospect of effective immunotherapies for the treatment of patients with cancer is now becoming a clinical reality. A basic understanding of interaction between the tumor and the immune system, immune regulation pathways, mechanisms of escape from immune control allows to identify and implement new therapeutic approaches for cancer treatment. This review provides a modern view on the formation of anti-tumor immunity. The role of the key players are discussed - the components of innate and adaptive immunity, the mechanisms of the immune response and their features.