Intraoperative radiotherapy in the combined treatment of breast cancer

The results of treatment of 120 patients with breast cancer using intraoperative radiotherapy (IORT) in combination with organ saving surgery and distant radiotherapy are given in this report. IORT was made on the Russian cyclic electron accelerator Microtron-M. The removed tumor bed area or axillary region was irradiated. The single focal irradiation dose was 10 Gy, while the accelerated electrons energy was 8 MeV. The obtained results analysis indicated that using of IORT doesn't increase the frequency of postoperational complications, radiation responses and injuries, extends the indications for organ saving operations on mammary gland, doesn't worsen the survival rate indices and can be considered as the alternative to the intensive preoperational irradiation.