Change of lactate dehydrogenase and its isoenzymes activity in blood of children and adolescents living in conditions of palne (Dagestan)

This study focuses on the activity of lactate dehydrogenase (LDH) and its isoenzymes in the blood in children and teenagers living in the plains of Dagestan (Makhachkala). The obtained results show that there is a certain pattern in a specific law in changing of LDH (total) and its isoenzymes activity in the blood in children and adolescents depending on the time of year. This pattern consists in the fact that LDG activity (total) in the autumn period is much higher in comparison with the spring period. In addition, there has been a significant decrease in LDH activity as children grow up (aged 7 to 17 years). The activity of LDH (total) isoenzymes in the blood of children and adolescents varies similarly to the total LDH activity in studied age periods, both in autumn and spring.