Changes in biochemical indicators of the blood of patients with fatal COVID-19

The study of the COVID-19 course is relevant due to the fact that this disease causes changes in biochemical indicators of blood in the human body. To analyze the age category of patients with COVID-19, distribution of patients by districts and regions in the Southern region, as well as associated disease factors in patients with COVID-19 with a fatal outcome. Research purpose: analysis of the age category of patients with COVID-19, distribution of patients by districts and regions of the Southern region, as well as concomitant disease factors in patients with fatal COVID-19. Research materials and methods: a descriptive study based on the analysis of electronic medical records of patients containing complete information about the course of the disease and data from standard laboratory and instrumental methods of examination in a hospital setting. Most of the patients with COVID-19 and pneumonia were admitted in Osh city or 65%, Karasuu district 14%, Uzgen district 7%, 4% Kara-Kulja district and 2% each Alai, Chon-Alai, Aravan districts and 2% each Batken and Jala-Abad regions. Conclusion: an increase in the absolute number of neutrophils (N), a decrease in the absolute number of lymphocytes (L) and, as a result, an increase in the N/L ratio index were markers of a more severe course of the disease.