Susceptibility to hypoxia and ventilatory responses to O2 and CO2 changes after short-term cold exposures

In 24 healthy young men were determined ventilatory sensitivity to hypoxia (HVR) and hypercapnic (HCVR) stimuli as indicators chemoreceptor regulation of the respiratory system, before and after the general short-term cooling (130, 2 hours, 10 days). Sensitivity to hypoxia (sSaO2) was determined by the rate of decline in hemoglobin oxygen saturation of arterial blood (SaO2) in the HVR test, when by the exponential decrease in the concentration of O2 in the inhaled air, SaO2 after a delay decreased linearly. Found that short-term general cooling is increased resistance to hypoxia in the high susceptibility to hypoxia group and reduced functional reserve in low susceptibility group. It accompanied by an increase in ventilatory response to O2 and CO2, the typical response to hypoxia. The selected groups did not differ on the HVR and HCVR before cooling.