The change in the parameters of nucleolar organizers in the cells of the renal tubules after partial nephrectomy when used for suturing the surgical wound filaments «Alloplant»

By using methods to identify regions of nucleolar organizers (Adao) with silver nitrate, the studied parameters, Adao in the cells of the renal tubules after partial nephrectomy using for suturing the surgical wound of the kidney thread «Alloplant» were studied. Studies have shown that Adao in the nuclei of cells of renal tubules of rabbits have a rounded or close to it in the shape, and the number of Adao is in the range from one to four. It was es-tablished that the greatest number of Adao in the nuclei of kidney tubular cells identified at the third day in a zone close to the scar (2.73±0.08) and lowest at the twelfth day was away from the rumen (1.80±0.04). The maximum increase of the total area of Adao recorded on the third day in the area of damage (4.76±0.18 µm2) and away from it (2.85±0.09 µm2), then there was a decrease of this parameter in the zone close to the scar to the fif-teenth day (2.93±0.10 µm2), and in the distance from it to the twelfth day (2.04±0.07 µm2). During the eighteenth and sixtieth days the value of this preoperative parameter approach, in the zone close to the surgical scar, and remote from him was in-vestigated. We obtained data on the dynamics of changes in the number of Adao in the nuclei of cells of renal tubules after partial nephrectomy co-incided with the dynamics of change of the total ar-ea of Adao. The research results indicated that in the thread «Alloplant» for suturing the surgical wound of the kidney after performing nephrectomy in the renal tubules, the change in the number and total area of Adao depending on proximity to the surgical scar that, in our opinion, reflected the dif-ferent proliferative potential of the cells of the renal tubules and the state of cellular differentiation.