Acoustic cognitive caused potentials (Р300)changes in chronic ischemia of brain

Cognitive infringements represent an actual problem of modern medicine. In elderly men they usually develop on a background of a chronic ischemia of brain (CHBI). Р300 research in 134 patients was carried out to define CHBI influence on the basic components of the caused potentials. The group of elderly patients with dyscircular encephalopathy I, II, III stages and group of middle-aged persons with presence CHBI and without attributes CHBI were considered. The increase of peaks N2, P3 latency, N2-P3 interpeak interval and decrease of N2/P3 amplitude in elderly patients with positive correlation are revealed depending on the stage of dyscircular encephalopathy. Latency increase and amplitude reduction of the basic components acoustic cognitive potential in middle-aged persons directly correlated with the CHBI presence.