Isotopes of carbon of amino acids in pathogenic biomineral formations

The influence of processes of a metabolism on isotope parities of biogenic elements in living organisms can be used for early diagnostics of different pathologies, but now remains poorly studied. The results on research of isotope composition of the carbon of amino acids of seven samples of the pathogenic biomineral formations generated in human organism (urolites and cholelites), differing on mineral structure, were received. The isotope structure of carbon of the received ethers of amino acids was determined by means of mass-spectrometer DeltaVAdvantage (Thermo) connected with gas chromatograph Trace GC Ultra (Thermo, capillary column DB-5) and system IsoLink. It was noticed that in crystal formations of the hydrocarbonic structure (a uric acid, a bilirubinate of calcium) the isotope structure of carbon of the majority of the studied amino acids was sinplified.