Examining safety of therapeutic clay “Undorovskaya”

The purpose of the paper is to study the mineralogical composition, and microbiological purity of the therapeutic clay “Undorovskaya” in order to solve the problem of its further use as an enterosorbent. Materials and Methods. Clay mineralogical composition was studied using an X-ray fluorescence spectrometer (ThermoNiton FXL, Thermoscientific, USA) with built-in software. Examination of microbiological purity was carried out according to the requirements of State Pharmacopoeia XIII, and general monograph GOFS.1.2.4.0002.15 “Microbiological purity”. Tests for acute and subchronic toxicity were conducted in accordance with GOST R-53434-2009 “Principles of Good Laboratory Practice” and the Order of the Ministry of Health and Social Development of the Russian Federation No. 708n “Good laboratory practice” (23.08.2010). Results. The content of heavy metals, and the microbiological purity of the therapeutic clay “Undorovskaya” met all the requirements of the current regulatory documents...