Study of the dependence of biomechanical and morphological properties of prosthetic alloplasty on the mesh implant suturing technique

Introduction. Due to the small number of scientific studies on alloplasty techniques for postoperative anterior abdominal wall hernias, there is still an urgent need to search for new techniques of anterior abdominal wall alloplasty, as well as the development and implementation of surgical mesh implants.The purpose of the study. Study of the dependence of biomechanical and morphological properties of prosthetic alloplasty on the mesh implant suturing technique.Materials and methods of research. 36 laboratory rats of Standard breed, weighing 400±50 g, were used as biological models in the experiment. In the conditions of acute experiment, the laboratory animals under general anesthesia in aseptic conditions underwent alloplasty with a mesh implant (Esfil, RF) according to the sublay technology. Two observation groups were formed (18 operated rats in each group) depending on the performed method of alloplasty. In the 1st group alloplasty with fixation of the implant with through U-shaped sutures was performed, whereas in Group 2 the implant was not fixed. On the 21-st day, material was collected for biomechanical and morphologic studies. The digital data obtained from the INSTRON-5944 bursting machine were processed by methods of variational mathematical analysis.Results. It was found that the difference in biomechanical indices after modeling prosthetic alloplasty with two different techniques (with and without fixation) was not statistically significant in the area of elastic-plastic deformations.Conclusion. In the course of biomechanical and morphological studies, it was proved that the strength of the abdominal wall in modeling posterior separation alloplasty does not depend on the method of fixation of the implant to the abdominal muscles.