The electrodiffusion of probing ions to biocolloids surface

The solution of the electrodiffusion problem that can be used in study of suspensions of cells and other particles (for example, liposomes), using probing ions, but also can be used in application-oriented tasks is proposed in this article. For example, in case of a medicines delivery study in cells or in case of a study of impact of short electrical pulses on cellular suspensions. It is supposed that duration of process of electrodiffusion is determined not by a pool of probing ions, but conditions on surfaces of particles, that are surface and electrokinetic potentials. In case of small times (less than one millisecond) the adsorption of probing ions is kinetically described as drift of ions in an electric field at a surface of a particle and in case of rather big times it is described as diffusion. The best values of probing ions concentration, when using such instrumental methods as the potentiometric and fluorescent analysis, are proved.