Epidemiological aspects the incidence of cancer of the kidney and bladder in Primorsky krai

Urinary system cancer is a malignancy caused by environmental exposures, the prevalence of which directly depends on the impact of environmental and anthropogenic factors. The aim of the study was to assess the kidney and bladder cancer incidence in different ecological and bioclimatic zones of Primorsky Krai. Material and methods. The incidence of kidney and bladder cancers in Primorsky Krai for the period between 1994 and 2014 was analyzed. In assessing the risk of kedney and bladder cancers in bioclimatic zones (marine climate, marine to continental transition and continental climate), environmental problems of the territories of Primorsky Krai were classified using the following ranks: critical, stress-like, satisfactory, and relatively favorable. The risk assessment was conducted using the guidance on Human Health Risk Assessment for Environmental Impact Assessment. To calculate the environmental impact on risk of urinary system cancer, the information entropy analysis was used. results. The territories with low, medium and high incidence of bladder and kidney cancers were identified. The high incidences of kidney and bladder cancers were registered in the territories with environmental problems ranked as critical and stress-like, affected by coal, mining and chemical industries, and in the territories with intensive use of chemical pesticides. The incidence of bladder cancer in men tended to rise from the continental bioclimatic zone to the coast in all ecological zones mainly due to differences in the structure of the bioclimate between the coast and continental areas of Primorsky Krai. The increased risk of urinary system cancer was shown to be associated with parameters, such as the quality of drinking water, total pollution of the environment, chemical composition of groundwater, and the sanitary condition of the soil. conclusion. The environmental risk assessment and ranking of territories by risk allow the cancer prevention and control programs to be developed and the need for increased cancer screening in certain areas to be identified.