Catestatin - a new of the cardiovascular system regulator (literature review)

Catestatin is a cationic and hydrophobic peptide derived from the enzymatic cleavage of the prohormone chromogranin A. Catestatin was first discovered in 1997 as a potent non-competitive and reversible inhibitor of catecholamine secretion. Accumulating evidence shows that catestatin is involved with cardiovascular diseases, performs important functions and can be used as a diagnostic biomarker. In this article, we review recent basic research and clinical trials in the study of catestatin and summarize the association of catestatin with cardiovascular diseases.