Clinical profile of Parkinson's disease in the Republic of Karelia

Clinical analysis of motor and non-motor phenomena in Parkinson’s disease (n = 140; in the course of the treatment: Levodopa, Pro- noran, Midantan) in the Republic of Karelia (2009-2013) showed that the onset of the disease is marked with combined non-motor dysfunctions: vegetative dysfunctions (vascular trophic, genitourinary, and dyspeptic dysfunctions; 97,9 %); sensory dysfunctions (dysosmia, pain syndrome); cognitive dysfunctions (35,7 %); high trait anxiety (51,4 %), which affects (k = 0,7, p 0,05). A “positive family history“ is typical only for the tremor form of Parkinson’s disease (p