Clinical importance of markers of renal dysfunction in cardio-vascular risk stratification

Purpose of the study. To study the significance of cystatin C of blood plasma and its relationship with central arterial pressure and carotid intima-media thickness (CIMT) in the stratification of cardiovascular risk. Materials and methods. A general clinical and laboratory examination of 206 patients aged 16 to 88 years was performed, of which men were 101 (49%), women - 105 (51%). The mean age of the examined subjects was 51.8±14.3 years. Lipid spectrum parameters [total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C)], cystatin C, plasma uric acid and fibrinogen were studied. Glomerular filtration rate (GFR) was calculated using the F.J. Hoek et al. (2003) formula. To assess the central blood pressure, all patients underwent a contour analysis of the pulse wave on the AngioScan-01 (AngioScan-Electronics, Russia) and ultrasound examination of carotid artery (CA) on Vivid Q (USA). The type of research was single-step cross-sectional...