Clinical and angiography efficacy of the paclitaxel-coated balloon coronary angioplasty in patients with in-stent restenosis

The present article shows the analysis of clinical and angiography efficacy of the paclitaxel-coated Balloon coronary angioplasty in patients with in-stent restenosis (ISR). In our study we included 90 endovascular interventions performed from 2008 to 2010 for the treatment of in-stent restenosis. The patients were classified into 2 equal groups based on an endovascular technique used. 35 patients (group I) were treated with a coronary balloon catheter coated with paclitaxel (SeQuent, BBraun; Dior, Eurocor).Patients from group II (n = 55) were revasculated with standard balloon angioplasty. Long-term outcome after angioplasty was assessed in 20 (57.2%) and 24 (43.6%) patients of the divided groups. The digital angiography was repeated within 6.4±0.11 months. Angiographic restenosis was revealed in 4 (20%) cases in group I and in 13 (54.2%) cases in group II. We revealed the decrease of angina pectoris middle functional class from 2.25±1.0 to 1.65±0.73 (p