Clinical and genetic risk factors for the development of hereditary nephritis in children in the conditions of the Fergana valley

In order to identify clinical and genetic risk factors for the development of hereditary nephritis in children in the Fergana Valley, we analyzed data from 168 case histories of children aged 1 to 14 years with a diagnosis of glomerulonephritis (acute-130 and chronic-38) for 2017- 2021, who received inpatient treatment in the children's multidisciplinary clinic of ASMI. It was found that in the conditions of the Ferghana Valley there is a tendency to increase the number of patients with urinary tract infections and dysmetabolic nephropathies of family origin. The incidence of hereditary nephritis is higher among patients with chronic glomerulonephritis than with acute glomerulonephritis and pyelonephritis. Algorithms for early diagnosis of hereditary nephritis in children include combined damage to the organs of hearing and vision, kidney diseases in several family members or among relatives.