Clinico-immunological appearances and disturbances of metabolism intracellular lymphocytes enzymes in patients with chronic lymphoid leukemia

We examined clinical-immunological state and estimated the activity of metabolic enzymes of lymphocytes in 57 pts chronic lymphoid leukemia. Rs chronic lymphoid leukemia in all disease's stages had immune status disturbances and changes of activities metabolic enzymes of lymphocytes. The most important immune status disturbances and changes of activities metabolic enzymes of lymphocytes in pts chronic lymphoid leukemia were revealed during terminal stage of disease. The revealed changes and differences characterize immunopathogenetic aspects developing and progressing of chronic lymphoid leukemia.