Clinical and morphological predictors of axillary lymph node metastases in women with breast cancer

The purpose of retrospective trial is assessment the impact of different clinical and pathological factors on axillary lymph node involvement in breast cancer patients. This data included patients’ age, localization of the primary tumor, traditional pathological criteria (primary tumor size, histological variant, grade, HR- and Her-2/neu status) and new total pathological index. Univariative regression analysis revealed that only tumor size (p=0.03) and total pathological index (p=0.00004) are the most powerful predictors of axillary lymph node involvement.