Contrast-induced acute kidney injury in patients with myocardial infarction non-obstruction and with coronary artery obstruction

Goal. To conduct a comparative assessment of renal function, risk factors and the incidence of contrast-induced nephropathy (CIN) in patients with MINOCA and MICAD, including taking into account the value of the left ventricular global function index (LVGFI).Material and methods. The study involved 170 patients diagnosed with myocardial infarction. The diagnosis was established in accordance with the Fourth Universal Definition. According to the results of coronary angiography (CAG), patients were divided into 2 groups: 1 - myocardial infarction without coronary artery obstruction (MINOCA), n=73,2 - myocardial infarction with coronary artery obstruction (MICAD), n=97, who, according to indications, underwent stenting of the infarct-associated coronary artery. According to the magnitude of the LVGFI, patients are divided into 2 subgroups: 1 - low LVGFI (31,2%). The glomerular filtration rate (GFR) was estimated according to the formula CKD - Epi 2011 at admission, 24 hours and 48 hours after the procedure. The CIN criterion is an increase in serum creatinine levels by 26,5 mmol/l or more within 48 hours after administration of an X-ray contrast agent (RVC).Results. In patients with MICAD, the risk of AKI CIN is the same. Patients with MICAD required a higher amount of PCI (89.8 ml, p31.2% required a larger volume of PCI (200 ml and 199 ml in patients with LVGFI function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }