Correlation features of oral mucosits and psychological status in patients with squamous cell carcinoma of the oral mucosa at the stage of chemoradiation therapy

Mucosits of the oral mucosa as a complication of cancer treatment remains an urgent problem. The risk of developing mucosits is classically directly related to the type, intensity of anticancer treatment, and type of psychological response. Combination therapy increases the severity of mucosits. The frequency of mucosits 3-4 degrees according to the WHO scale reaches 85 % and is considered severe among patients receiving high-dose radiation therapy to the head and neck area. In squamous cell carcinoma of the oral mucosa, oral mucosits is the main limiting factor in chemo radiation therapy.It is often necessary to resort to enteral nutritional support and the use of morphine-type analgesics to complete the planned exposure, or to interrupt therapy. In order to prevent mucosits, we studied the correlation between its degree and psychological reactions. The studied psychosomatic status of patients with squamous cell carcinoma of oral mucosa, who are at the stage of chemoradiation therapy, complicated by mucosits, showed a direct relationship between these indicators.