Markers of endothelial dysfunction as a prognostic sign of intracardiac infectious flow process

The results of studies of markers of endothelial dysfunction (ED) in 35 patients with acquired heart defects, including 23 with infective endocarditis, have been presented. ED evaluation has been performed before surgery, immediately after and 10-12 days after surgery. The obtained data indicate severe endothelial dysfunction in patients with infective endocarditis (IE). After surgery, there is a sharp increase in markers of ED in both groups. In patients with IE with adequate sanitation and antimicrobial therapy, normalization of endothelial function occurs after 12-15 days.