Metabolic activity of intestinal microflora in early children

In recent years, a promising method for assessing the state of microflora has been developed - the method of gas-liquid chromatography (GLC), based on the determination of metabolites of the indigenous flora - volatile fatty acids (VFA) in feces in the intestine. In the literature, there are isolated works devoted to the clinical assessment of the GLC method for AEI of viral etiology in children, in which the correlation of intestinal dysbiosis and the content of various VFAs in coprofiltrate was analyzed. However, to date, there is no consensus on the diagnostic and prognostic role of changes in the metabolic activity of the anaerobic flora in AEI in children, biochemical markers of dysbiotic disorders in diarrhea of different etiology have not been determined, and the effectiveness of metabolic approaches to the correction of intestinal dysbiosis in viral diarrhea has not been evaluated.