Methods of extracorporal immunopharmacotherapy: from general clinical practice - to the oncological

The review presents the results of applying extracorporeal immunopharma-cotherapy (EIPHT) techniques in medical practice for the treatment of infectious, autoimmune diseases, as well as septic complications. Studies of EIPHT as an accompanying therapy in the treatment of malignant tumors are presented. The wide practical implementation of EIPHT is hampered by insufficient clinical approbation for various diseases, a small spectrum of studied drugs, the lack of adequate methods for predicting efficacy. In her own studies on the example of patients with cervical cancer II-III stages, it was shown that the most effective in complex treatment is the scheme of immunotherapy, including intermittent plasmapheresis followed by EIPHT, which improves blood levels, increases leukemia and lymphopoiesis, normalizes the parameters of cellular and humoral immunity, reduces the main clinical manifestations of toxicity of chemotherapy, improves the indicators of the subjective state of patients and their quality of life, and also increases the indicators of the heel year survival rate.