Interethnic associations of increased heart rate as a factor of cardiovascular risk. Part 1: сlinical markers

Purpose. To evaluate the association of clinical factors of cardiovascular risk with an increased heart rate (HR) in the population of Mountain Shoria, depending on ethnicity.Material and Methods. The study involved residents of the villages of Mountain Shoria aged 18 years and older. Included are 901 people - representatives of indigenous nationality (Shors), 408 people - of nonindigenous nationality. The groups did not differ by gender and age. The analysis was carried out depending on the increased level of heart rate (over 80 beats/min). As markers, we analyzed the factors used to stratify the overall cardiovascular risk.Results. In the population of Mountain Shoria, the prevalence of tachycardia was 21.1%: 19.3% among Shors and 24.2% among non-indigenous people (p = 0.030). Interethnic differences in increased heart rate were determined by the following cardiovascular risk factors: male gender, smoking, hypertriglyceridemia, low levels of high density lipoprotein cholesterol and high low-density lipoprotein cholesterol. The risk of this pathology, both in the group of Shors and non-indigenous people, was increased in individuals with arterial hypertension [OR = 3.50; 95% CI (2.31-5.32) and OR = 4.06; 95% CI (2.37-6.95)] and diabetes mellitus [OR = 2.10; 95% CI (1.19-3.72) and OR = 2.64; 95% CI (1.33-5.27)], respectively. In addition, the odds ratio for tachycardia increased among indigenous people who abuse alcohol [OR = 1.60; 95% CI (1.01-2.60)]; among representatives of an indigenous ethnic group with hypertriglyceridemia [OR = 1.86; 95% CI (1.19-2.93)].Conclusions. Ethnic features of associative relationships between tachycardia and cardiovascular risk factors have been established. A wide range of markers associated with increased heart rate suggests a further more detailed study of these relationships.