Vaginal microbiota and myomatous nodes in term of full term pregnancy

The aim of the study was to study the qualitative and quantitative composition of the vaginal microbiota, the myomatous node, its bed and intact myometrium in patients with full term pregnancy. Materials and methods: a total of 12 women with a terminated pregnancy and verified uterine fibroids with subserous or interstitial-subserous localization from 5 cm in diameter were studied. All patients were comparable in age, height, weight, obstetric-gynecological anamnesis and the presence of concomitant extragenital pathology. All patients are delivered by caesarean section with simultaneous myomectomy. Antibiotics and sanation of the vagina during pregnancy was not conducted. All patients were sampled from the vaginal posterior vestibule in the morning before surgery, biopsy of myoma nodes, their bed and intact myometrium - intraoperatively. Results: In the examined patients with uterine myoma the main symbionts of the vagina Lactobacillus spp. were found in 8.3% of cases, while Eubacterium spp. were found in 100% of cases. Despite the low frequency of detection of lactobacilli in the vagina, pregnant women had no complaints and clinical signs of inflammation. The myomatous node, its bed and intact myometrium are in most cases not sterile at 83.3%; 92.7%; 66.7% respectively. The studied loci are dominated by nonclostridial-anaerobic bacteria. Fusobacterium spp., Bacteroides spp., Propionibacteriums spp. were found in all the studied patients in the myomatous node, its bed and intact myometrium.