Bone mineral density and bone turnover markers in osteoarthrosis accompanied by osteodeficiency conditions (review)

Objective: to define bone mineral density and bone turnover indicators in primary osteoarthrosis accompanied with osteodeficiency conditions of varying severity as a means of early osteoarthrosis detection in individuals. Review method. We analyzed 157 Russian and foreign studies of 2005-2022 retrieved from e-Library, Medline, PubMed, PubMed Central, Google Scholar, SpringerLink и Elsevier. The keyword search in Russian and English involved "primary osteoarthritis", "osteoporosis", "osteopenia", "bone mineral density", "markers of bone resorption", "bone formation markers", "bone metabolism regulators", "RANKL/RANK/OPG system". 35 studies were considered the most valuable and eventually reviewed.