Philosophical significance of diagnostics theory

The diagnostics theory covers the clinical experience of century-old medicine. A clinical study should begin with the fundamentals of the diagnostics theory, which is equally important both for a practitioner and a medical scientist. Despite significant advances in modern medicine due to the development of new technologies, the priority of clinical examination of patient is strengthened. Nowadays the most important pathology theories developed in the end of 19 th and beginning of 20 th centuries are being tested clinically. A deeper research at the molecular level results in disappearance of the clinical specificity of diseases. The inflammatory nature of the pathological process and the generalization of the changes in cell membranes, including CNS, are now increasingly found in the pathogenesis of diseases of internal organs. It is highly probable that the specific presentation of clinical entities is determined by the changes in membranes in various parts of CNS. The etiology of diseases with autoimmune pathogenesis remains a mystery, with the vector of the dialectical relationship between conditionalism and monocausalism shifting toward the latter, in particular, to determining the infectious nature of disease. Challenging problem is the contradiction between the methodical and methodological levels of studying physiological and pathological processes in the human organism. The paradoxes observed in the relationship between theories and clinical manifestations of pathology must generate new hypotheses and the need to test them in the experiment.