Different chrome sources influence on morpho-biochemical indicators and activity of digestive enzymes in Wistar rats

Nowadays, issues of mineral nutrition of humans and animals are quite relevant. High-energy rations, multicomponent feed mixtures and additives in the diets require special attention when optimizing limited microelements. A priori, chromium, being an important trace element in animals, is used to correct carbohydrate, fat and lipid metabolism. Due to its low content in the components of diets, its role in the formation of the microecological status of the body is poorly understood. At the same time, its biological availability in the body depends on the source of chromium. In the present work, using a model object, the Wistar rats, we for the first time compared the biological effects of various chromium sources, i.e. picolinate (CrPic), nanoform (NP Cr2O3) and chloride (CrCl3) at doses of 300 and 500 μg/kg feed, according to a set of indicators (feed digestibility, hematological parameters, activity of digestive enzymes, composition of intestinal microflora) and established greater bioavailability and more pronounced positive effect of picolinate and chromium nanoparticles on body weight and hematological parameters and ambiguous influence of the studied forms on the activity of digestive enzymes and intestinal microflora...