Non-invasive mass spectrometric method of measurement skin secretion CO2

The possibility of using a mass spectrometer with a membrane interface for a non-invasive measurement of the skin secretion CO2 of a healthy human. As a result, the technique of percutaneous measurement at the level of the upper third of the forearm of the upper limbs was developed, and the reproducibility of the results was analyzed. Calibration of measuring equipment was carried out and experimental clinical measurements were carried out. The results obtained are analyzed and given a substantive interpretation. The developed method can be recommended for implementation in clinical practice.